Nature s Secrets Rexetin

In case of obsessive-compulsive disorder: the initial dose is 20 mg / day. The dose may be increased by 10 mg weekly until the desired therapeutic response is achieved. The maximum daily dose is usually 40 mg, but should not exceed 60 mg.

Depending on the clinical condition of the patient, maintenance therapy is necessary to prevent possible relapses. This race after the disappearance of symptoms of depression can be 4-6 months, and with obsessive and panic disorders and more. As with other psychotropic drugs, abrupt cessation of treatment should be avoided. In weakened and elderly patients, the recommended initial dose is 10 mg / day. This dose may be increased by 10 mg weekly, depending on the patient's condition.

In case of social phobia: therapy can be started with a dose of 20 mg / day. If after a 2-week course of treatment there is no significant improvement in the patient's condition, the dose of the drug may be increased by 10 mg to achieve the desired effect. The maximum daily dose should not exceed 50 mg. For maintenance therapy, a daily dose of 20 mg is usually sufficient..

As with other antidepressant therapy, depending on the patient's clinical condition, the dosage of the drug can be changed after 2-3 weeks.

Paroxetine should be used with caution if there is a history of epilepsy. According to clinical observations, paroxetine causes epileptiform seizures in 0.1% of patients. It is necessary to interrupt the treatment of patients who have manifested such disorders.

The concentration of paroxetine in blood plasma increases with the liver and kidney function, as well as in the elderly.

The drug was prescribed for long-term depersonalization and derealization, accompanied by a depressive episode, also longer-term, more than 1.5 years. Well relieved symptoms at the 2nd month of admission, while losing weight. But it was taken in combination with other drugs, so it is hard to say if it would have acted with monotherapy. During the intake, sleep time has increased to 15-16 hours for the first months. At the end of the meal, sleep time was normal. After termination of the administration, side effects appeared, despite a reduction in dosage and a gradual withdrawal of the drug. I observed a loss of balance.

I have a completely different opinion about this drug. She took a job with the doctor, withstood exactly one week. Panic attacks only intensified, as a side effect of a strong derealization. But I emphasize, this is my individual reaction to Rexetin. It is strange to read that the patient's condition improves in the first few days. For that matter, Rexetin, like any SSRI, takes time to take action. The dosage is increased, monitoring the patient's condition. But this is not a problem, but doctors who do not properly paint the regimen of the drug. The drug is not bad, but not for everyone. Try, but under the guidance of an experienced psychotherapist or psychiatrist.

Side effects of the drug are most pronounced at the beginning of therapy, however, during treatment, their intensity and frequency of occurrence decrease. In patients, the following side effects: headache, dizziness, impaired sleep and wakefulness, drowsiness, trembling limbs, fatigue, irritability, paresthesia. Extrapyramidal states, orofacial dystonia, convulsions are extremely rare. Dry mouth, excessive sweating, disturbances in the visual system. From the cardiovascular system: cardiac arrhythmias, changes in blood pressure, changes in the electrocardiogram, vasodilation, and fainting. From the gastrointestinal tract: nausea, vomiting, stool disorders (both constipation and diarrhea are possible), increased activity of liver enzymes, decreased appetite, impaired liver function. From the genitourinary system: disorders of ejaculation, decreased libido, difficulty urinating. From the skin: hyperemia of the skin, hematoma. Allergic reactions: skin itching, rash, urticaria, swelling of the face and limbs, bronchospasm, Quincke's edema. Other side effects: imbalance electrolyte, in particular hyponatremia, increased synthesis of antidiuretic hormone. Myopathy, myalgia, hyper-or hypoglycemia, galactorrhea, flu-like symptoms, thrombocytopenia.

Coated tablets, 20 mg of active ingredient, 10 pieces each in a blister, 3 blisters in a cardboard box. Coated tablets, 30 mg of active ingredient, 10 pieces each in a blister, 3 blisters in a cardboard box.

Paroxetine increases the concentration of lithium in blood plasma. Drugs that affect the activity of liver enzymes can alter the metabolism of paroxetine. Rexetine with simultaneous use of the metabolic rate of antidepressants, phenothiazines, antiarrhythmic drugs, as well as quinidine, cimetidine and codeine. Phenobarbital with simultaneous use accelerates the excretion of paroxetine and reduces its concentration in blood plasma. Antiepileptic drugs increase the manifestation of side effects of paroxetine. The drug increases plasma concentrations of procyclidine, theophylline. The drug is not recommended to be used with ethanol..

Like other selective serotonin reuptake inhibitors (SSRIs), paroxetine causes mydriasis, therefore, in the presence of glaucoma, the drug should be used with caution.

There is no reliable clinical data on the inhibition of CYP3A4 isoenzyme by paroxetine, therefore, it is possible to use with drugs that inhibit this enzyme (for example, terfenadine).

Paroxetine is contraindicated simultaneously with MAO inhibitors and within 14 days after withdrawal. In the future, paroxetine should be used with extreme caution, starting a course of treatment with small doses and increasing the dosage to achieve the desired therapeutic effect. After treatment with paroxetine for 14 days, you can not start with MAO inhibitors.

Paroxetine hydrochloride (a derivative of Paroxetine) is reported as an ingredient of Rexetin in the following countries:

Paroxetine hydrochloride hemihydrate (a derivative of Paroxetine) is reported as an ingredient of Rexetin in the following countries:

Recently, there is clinical evidence that the indications for use can be expanded with medical treatment of sociophobia. So pharmaceutical studies have confirmed that with active conservative therapy, you can achieve the same positive results as a constant with a psychiatrist, because earlier it was the only scheme for the rehabilitation of mentally ill sociophobia.

It is worth noting that paroxetine, as the main chemical component of the drug, also has an anxiolytic effect, since it is primarily associated with increased excitability of the subcortical structures of the brain, to which the active component of Rexetin spreads. Due to the formation of the central nervous system, the thalamus and hypothalamus, the manifestations of anxiety are reduced.

After taking the pill orally (orally), the pharmacological drug is rapidly absorbed in the gastrointestinal tract. Eating does not significantly affect the absorption capacity of Rexetin. The drug has a high degree of binding to plasma proteins (about 93-95 percent of paroxetine), which ensures prolonged circulation of the active components in the bloodstream.

It is available in the form of tablets coated with a film coating: almost white or white, round, biconvex, on one side is risk, on the other is engraving "X20" or "X30" (10 pcs. cardboard bundle 3 blisters and Rexetin instructions for use).

Depression: 20 mg, as a rule, the effect develops gradually. In some cases, it is necessary to increase the dose of the drug (per week - by 10 mg, until the therapeutic effect is achieved). Maximum - 50 mg per day; Sociophobia: 20 mg, if after 14 days of therapy there is no improvement, the dose is gradually increased to achieve the desired effect. Maximum - 50 mg per day. As maintenance therapy, Rexetine is prescribed at 20 mg per day; Panic Disorders: 10 mg (due to increase in the intensity of the symptoms of the disease at the beginning of treatment) with a gradual (10 mg 1 time per week) increase to 40 mg. Maximum - 60 mg per day; Obsessive-compulsive disorder (obstruction syndrome): 20 mg, possibly a gradual (10 mg) increase in dose. Maximum - 40-60 mg; Generalized anxiety and post-traumatic stress disorders: 20 mg, possibly a gradual (10 mg once a week) increase to a daily dose of 50 mg.

Like other serotonin reuptake inhibitors, an undesirable interaction between MAO inhibitors and paroxetine was observed in animal experiments.

Paroxetine hydrochloride (a derivative of Paroxetine) is reported as an ingredient of Rexetin in the following countries:

Paroxetine hydrochloride hemihydrate (a derivative of Paroxetine) is reported as an ingredient of Rexetin in the following countries:

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